when i do a presentation, i am too sensitive to the audience. every single twitch, every single yawn (ok, it's not THAT bad), every single bored look, will set me back, will make me be unsure of myself. this will result in the sudden drop of self confidence level, which then will adversely impact my presentation, because i don't trust myself, because i dont' have confidence in myself.
i've seen other confident speakers that somehow weaves the magic, that somehow manage to persuade others to listen attentively. sometimes the audiences look bored, but after a while the speaker will be able to dispel that, and make the audiences laugh.